Research

I currently work with focused ultrasound, a technology used to perform non-invasive brain surgery in humans. I also have experience in medical imaging, image processing, and nuclear medicine.

Focused ultrasound

Improving noninvasive brain surgery

Noninvasive brain surgery using focused ultrasound is already being performed in hospitals, though targeting structures inside the brain can still be improved. Using the rapid beam simulation framework I previously developed, I showed that the technique provides great promise for improving treatment outcomes

Focused ultrasound

A rapid beam simulation framework

Focused ultrasound is used in noninvasive brain surgery to heat up and destroy brain tissue. Before doing irreversible damage, the surgeon would like to know where the focal spot is. I've developed a simulation framework that predicts where the focal spot will be and how hot it will be, with the potential to be used in real-time during treatments

Neurosurgery

Understanding complications of laser thermal therapy

Laser interstitial thermal therapy is a minimally invasive therapy for treating medication-resistant epilepsy. There have been several cases of adverse complications due to this therapy, and in this work we investigated the likely causes of these complications

Nuclear medicine

Individualized estimates of radiation exposure

Patients who undergo positron emission tomography imaging are exposed to ionizing radiation. However, patients' exposure to radiation is not well quantified. In a push towards personalized medicine, we performed estimations of radiation exposure on a patient-specific basis

Focused ultrasound

Understanding acoustic velocity in skull bone

Accurate simulations of ultrasound propagation depend on accurate simulation parameters. The skull is a highly complex medium that distorts the ultrasound focal spot and displaces it away from the target. We performed empirical measurements of acoustic velocity in human skull bone in order to improve simulation accuracy

Focused ultrasound

Understanding attenuation in skull bone

Accurate simulations of ultrasound propagation depend on accurate simulation parameters. The skull is a highly complex medium that distorts the ultrasound focal spot and displaces it away from the target. We performed empirical measurements of attenuation in human skull bone in order to improve simulation accuracy